NMS-P945

NMS-P945 serves as an ADC linker suitable for the synthesis of antibody-drug conjugates (ADCs) . It is adept at coupling to monoclonal antibodies (mAbs), consistently achieving a Drug Antibody Ratio (DAR) greater than 3.5 [1].

C(Cl)[C@H]1C2=C(N(C(=O)C3=CC=4C(N3)=CC=C(OCCN5CCCC5)C4)C1)C=C(OC(N(CCN(C(OCC6=CC=C(NC([C@@H](NC([C@@H](NC(CCCCCN7C(=O)C=CC7=O)=O)C(C)C)=O)CCCNC(N)=O)=O)C=C6)=O)C)C)=O)C8=C2C(C)=CS8