BCN-HS-PEG2-VA-PABC-SG3199
Product Specifications
CAS Number
2126805-05-6
Target
ADC Linker
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
BCN-HS-PEG2-VA-PABC-SG3199 (Compound 4) functions as a pyrrolobenzodiazepine-based agent linker for antibody-drug conjugates (ADC) [1]. This compound also serves as a click chemistry reagent, featuring a BCN group capable of participating in strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules.
Smiles
C(OCC1=CC=C(NC([C@@H](NC([C@@H](NC(COCCOCCNS(NC(OC[C@@H]2[C@]3([C@@]2(CCC#CCC3)[H])[H])=O)(=O)=O)=O)[C@@H](C)C)=O)C)=O)C=C1)(=O)N4C=5C(C(=O)N6[C@]([C@@H]4O)(CC(C)=C6)[H])=CC(OC)=C(OCCCCCOC7=C(OC)C=C8C(=C7)N=C[C@]9(N(C8=O)C=C(C)C9)[H])C5
Molecular Formula
C66H83N9O18S
Molecular Weight
1322.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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