(1S,9R) -Exatecan mesylate
Product Specifications
CAS Number
2938875-54-6
Target
ADC Cytotoxin, Topoisomerase
Related Pathways
DNA Damage/DNA Repair, Antibody-drug Conjugate/ADC Related
Bioactivity
(1S,9R) -Exatecan Mesylate ((1S,9R) -DX8951f) serves as an isomer of Exatecan Mesylate (DX8951f), which acts as a DNA topoisomerase I inhibitor with an IC50 value of 2.2 μM (0.975 μg/mL) . This compound is utilized in the field of cancer research [1].
Smiles
S(C)(=O)(=O)O.N[C@@H]1C2=C3C(C=4N(C3)C(=O)C5=C(C4)[C@@](CC)(O)C(=O)OC5)=NC=6C2=C(CC1)C(C)=C(F)C6
Molecular Formula
C25H26FN3O7S
Molecular Weight
531.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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