Dox-btn2

Antibody-drug Conjugate/ADC Related, Apoptosis, Autophagy, Microbiology/Virology, Chromatin/Epigenetic, DNA Damage/DNA Repair, PI3K/Akt/mTOR signaling, Proteases/Proteasome

Dox-btn2, a biotinylated derivative of Doxorubicin with a biotin label attached at the 3'-NH2 position, can be utilized for cell imaging. Unlike Doxorubicin, which primarily accumulates in the nucleus, Dox-btn2 is predominantly found in the cytoplasm [1].

OC=1C2=C([C@@H](O[C@H]3C[C@H](NC(CCOCCOCCOCCOCCNC(CCCC[C@H]4[C@@]5([C@](CS4)(NC(=O)N5)[H])[H])=O)=O)[C@H](O)[C@H](C)O3)C[C@@](C(CO)=O)(O)C2)C(O)=C6C1C(=O)C=7C(C6=O)=C(OC)C=CC7