Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Mal
Product Specifications
CAS Number
2345732-83-2
Target
Drug-Linker Conjugates for ADC, Glucocorticoid Receptor
Related Pathways
Endocrinology/Hormones, Antibody-drug Conjugate/ADC Related
Bioactivity
Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Mal functions as a glucocorticoid receptor agonist and serves as a drug-linker conjugate for ADC. This compound is instrumental in the synthesis of anti-CD40 antibody agent conjugates (WO2019106608A1; example 9) [1].
Smiles
C(COP(=O)(O)O)(=O)[C@]12[C@]3(C)[C@@](C[C@]1(O[C@H](O2)C4=CC=C(CC5=CC(NC([C@@H](NC(CN6C(=O)C=CC6=O)=O)CCC(O)=O)=O)=CC=C5)C=C4)[H])([C@]7([C@]([C@@H](O)C3)([C@]8(C)C(CC7)=CC(=O)C=C8)[H])[H])[H]
Molecular Formula
C46H50N3O15P
Molecular Weight
915.87
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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