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Val-Cit-PAB-DEA-Dxd

Product Specifications

CAS Number

2964543-53-9

Target

Drug-Linker Conjugates for ADC

Related Pathways

Antibody-drug Conjugate/ADC Related

Bioactivity

Val-Cit-PAB-DEA-Dxd (compound 81) serves as a Drug-Linker Conjugate for Antibody-Drug Conjugates (ADCs), comprising a linker coupled with the cytotoxic agent Dxd, a DNA topoisomerase I inhibitor. This compound is utilized in the synthesis of ADCs [1].

Smiles

N(C(COC(N(CCN(C(OCC1=CC=C(NC([C@@H](NC([C@H](C(C)C)N)=O)CCCNC(N)=O)=O)C=C1)=O)C)C)=O)=O)[C@@H]2C3=C4C(C=5N(C4)C(=O)C6=C(C5)[C@](CC)(O)C(=O)OC6)=NC=7C3=C(CC2)C(C)=C(F)C7

Molecular Formula

C50H61FN10O12

Molecular Weight

1013.08

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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