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2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-Exatecan

Product Specifications

CAS Number

2964536-59-0

Target

Drug-Linker Conjugates for ADC, Topoisomerase

Related Pathways

DNA Damage/DNA Repair, Antibody-drug Conjugate/ADC Related

Bioactivity

2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-Exatecan is a drug-linker conjugate for ADCs, featuring a cleavable linker coupled to Exatecan. This specific compound can be conjugated to the anti-Her3 antibody [1].

Smiles

N(C(COCNC(CNC([C@H](CC1=CC=CC=C1)NC(CNC(CNC(CCCC#CC=2C=NC(S(C)(=O)=O)=NC2)=O)=O)=O)=O)=O)=O)[C@@H]3C4=C5C(C=6N(C5)C(=O)C7=C(C6)[C@](CC)(O)C(=O)OC7)=NC=8C4=C(CC3)C(C)=C(F)C8

Molecular Formula

C53H55FN10O13S

Molecular Weight

1091.13

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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