NHS-Ala-Ala-Asn-active metabolite

NHS-Ala-Ala-Asn-active metabolite serves as a cleavable linker in the synthesis of antibody-drug conjugates (ADCs) targeting kinesin spindle protein (KSP) inhibitors [1].

[C@@H](N(CC[C@H](NC([C@@H](NC([C@@H](N(C([C@@H](NC(CCCC(ON1C(=O)CCC1=O)=O)=O)C)=O)C)C)=O)CC(N)=O)=O)C(NCCC(N[C@H](CCC(O)=O)C(O)=O)=O)=O)C(CO)=O)(C(C)(C)C)C=2N(CC3=CC=CC=C3)C=C(C2)C4=C(F)C=CC(F)=C4