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NHS-Ala-Ala-Asn-active metabolite

Product Specifications

CAS Number

2231135-69-4

Target

ADC Linker, Kinesin

Related Pathways

Cytoskeletal Signaling, Antibody-drug Conjugate/ADC Related

Bioactivity

NHS-Ala-Ala-Asn-active metabolite serves as a cleavable linker in the synthesis of antibody-drug conjugates (ADCs) targeting kinesin spindle protein (KSP) inhibitors [1].

Smiles

[C@@H](N(CC[C@H](NC([C@@H](NC([C@@H](N(C([C@@H](NC(CCCC(ON1C(=O)CCC1=O)=O)=O)C)=O)C)C)=O)CC(N)=O)=O)C(NCCC(N[C@H](CCC(O)=O)C(O)=O)=O)=O)C(CO)=O)(C(C)(C)C)C=2N(CC3=CC=CC=C3)C=C(C2)C4=C(F)C=CC(F)=C4

Molecular Formula

C56H72F2N10O17

Molecular Weight

1195.22

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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