NHS-Ala-Ala-Asn-active metabolite
Product Specifications
CAS Number
2231135-69-4
Target
ADC Linker, Kinesin
Related Pathways
Cytoskeletal Signaling, Antibody-drug Conjugate/ADC Related
Bioactivity
NHS-Ala-Ala-Asn-active metabolite serves as a cleavable linker in the synthesis of antibody-drug conjugates (ADCs) targeting kinesin spindle protein (KSP) inhibitors [1].
Smiles
[C@@H](N(CC[C@H](NC([C@@H](NC([C@@H](N(C([C@@H](NC(CCCC(ON1C(=O)CCC1=O)=O)=O)C)=O)C)C)=O)CC(N)=O)=O)C(NCCC(N[C@H](CCC(O)=O)C(O)=O)=O)=O)C(CO)=O)(C(C)(C)C)C=2N(CC3=CC=CC=C3)C=C(C2)C4=C(F)C=CC(F)=C4
Molecular Formula
C56H72F2N10O17
Molecular Weight
1195.22
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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