4-Pentynoyl-Val-Ala-PAB-PNP
Product Specifications
CAS Number
1956294-76-0
Target
ADC Linker
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
4-Pentynoyl-Val-Ala-PAB-PNP, a cleavable ADC linker used for synthesizing cryptophycin conjugates [1], is a click chemistry reagent that contains an alkyne group. It can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups.
Smiles
O(C(OCC1=CC=C(NC([C@@H](NC([C@@H](NC(CCC#C)=O)C(C)C)=O)C)=O)C=C1)=O)C2=CC=C(N(=O)=O)C=C2
Molecular Formula
C27H30N4O8
Molecular Weight
538.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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