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4-Pentynoyl-Val-Ala-PAB-PNP

Product Specifications

CAS Number

1956294-76-0

Target

ADC Linker

Related Pathways

Antibody-drug Conjugate/ADC Related

Bioactivity

4-Pentynoyl-Val-Ala-PAB-PNP, a cleavable ADC linker used for synthesizing cryptophycin conjugates [1], is a click chemistry reagent that contains an alkyne group. It can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups.

Smiles

O(C(OCC1=CC=C(NC([C@@H](NC([C@@H](NC(CCC#C)=O)C(C)C)=O)C)=O)C=C1)=O)C2=CC=C(N(=O)=O)C=C2

Molecular Formula

C27H30N4O8

Molecular Weight

538.55

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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