TCO-PEG3-CH2-aldehyde

TCO-PEG3-CH2-aldehyde, a cleavable 3-unit PEG ADC linker, is employed in the construction of antibody-drug conjugates (ADCs) [1]. This compound serves as a click chemistry reagent and features a TCO group capable of participating in an inverse electron demand Diels-Alder reaction (iEDDA) with molecules that contain Tetrazine groups.