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DBCO-PEG3 acetic-EVCit-PAB

Product Specifications

CAS Number

2253947-17-8

Target

ADC Linker

Related Pathways

Antibody-drug Conjugate/ADC Related

Bioactivity

DBCO-PEG3 acetic-EVCit-PAB, a cleavable 3-unit PEG ADC linker, plays a crucial role in the synthesis of antibody-drug conjugates (ADCs) [1]. This compound features a DBCO group, enabling it to engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-bearing molecules, and is also utilized as a click chemistry reagent.

Smiles

C(CCC(NCCOCCOCCOCC(N[C@H](C(N[C@H](C(N[C@H](C(NC1=CC=C(CO)C=C1)=O)CCCNC(N)=O)=O)C(C)C)=O)CCC(OC(C)(C)C)=O)=O)=O)(=O)N2C=3C(C#CC=4C(C2)=CC=CC4)=CC=CC3

Molecular Formula

C54H72N8O13

Molecular Weight

1041.2

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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