TCO-GK-PEG4-NHS ester
Product Specifications
CAS Number
2307311-19-7
Target
ADC Linker
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
TCO-GK-PEG4-NHS ester serves as an ADC linker, suitable for synthesizing [18F] AlF-NOTA-Tz-TCO-GK-2Rs15d, which demonstrates high affinity and immunoreactivity to HER2 [1]. This compound is a click chemistry reagent containing a TCO group that can engage in an inverse electron demand Diels-Alder reaction (iEDDA) with Tetrazine-containing molecules.
Smiles
O(C(CCOCCOCCOCCOCCC(NCCCC[C@H](NC(CNC(OC1CCCC=CCC1)=O)=O)C(O)=O)=O)=O)N2C(=O)CCC2=O
Molecular Formula
C33H52N4O14
Molecular Weight
728.78
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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