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10NH2-11F-Camptothecin TFA

Product Specifications

CAS Number

2873461-64-2

Target

ADC Cytotoxin|||Topoisomerase

Related Pathways

DNA Damage/DNA Repair|||Antibody-drug Conjugate/ADC Related

Bioactivity

10NH2-11F-Camptothecin TFA, a Camptothecin analogue, functions as an ADC cytotoxin for antibody-drug conjugates (ADCs) synthesis. It exhibits anticancer properties (WO2022246576A1; compound 140) [1].

Smiles

C(C(O)=O)(F)(F)F.C(C)[C@]1(O)C2=C(C(=O)N3C(=C2)C=4C(C3)=CC=5C(N4)=CC(F)=C(N)C5)COC1=O

Molecular Formula

C22H17F4N3O6

Molecular Weight

495.38

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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