STING agonist-35
Product Specifications
CAS Number
2228891-94-7
Target
ADC Cytotoxin, STING
Related Pathways
Antibody-drug Conjugate/ADC Related, Immunology/Inflammation
Bioactivity
STING agonist-35 (Compound 1a) is an agonist for stimulator of interferon genes (STING), activating wild type STING and mutated type STING (R232H) at rates of 99% and 92%, respectively. It is a potent payload for ADC [1].
Smiles
OC1[C@]2([H])[C@H](N3C4=C(C(N=CN4)=O)C(F)=C3)O[C@]1([H])COP([S-])(O[C@]5([H])[C@@](O[C@@H](N6C7=NC=NC(N)=C7N=C6)[C@@H]5F)([H])COP(O)(O2)=O)=O.[Na+]
Molecular Formula
C21H20F2N8Na2O11P2S
Molecular Weight
738.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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