(1R,9R) -Exatecan mesylate
Product Specifications
CAS Number
2938875-39-7
Target
ADC Cytotoxin
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
(1R,9R) -Exatecan mesylate ((1R,9R) -DX8951f) is an isomer of Exatecan mesylate, an inhibitor of DNA topoisomerase I with an IC50 of 2.2 μM (0.975 μg/mL), and useful in cancer research [1].
Smiles
S(C)(=O)(=O)O.N[C@H]1C2=C3C(C=4N(C3)C(=O)C5=C(C4)[C@@](CC)(O)C(=O)OC5)=NC=6C2=C(CC1)C(C)=C(F)C6
Molecular Formula
C25H26FN3O7S
Molecular Weight
531.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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