MC- (β-Ala) -PABC- (β-D-GlcUA) -amide-PEG1-CH2-CC-885

MC- (β-Ala) -PABC- (β-D-GlcUA) -amide-PEG1-CH2-CC-885 (Comp Ie) serves as a neodegrader conjugate instrumental in the synthesis of antibody neoDegrader conjugate (AnDC) [1].

O=C1C=2C(CN1C3C(=O)NC(=O)CC3)=CC(CNC(NC4=CC(Cl)=C(CCOCCN(C(OCC5=CC(NC(CCNC(CCCCCN6C(=O)C=CC6=O)=O)=O)=C(O[C@@H]7O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]7O)C=C5)=O)C)C=C4)=O)=CC2