PBD-monoamide
Product Specifications
CAS Number
2093165-00-3
Target
ADC Cytotoxin
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
PBD-monoamide, a modified pyrrolobenzodiazepine (PBD) dimer, functions as an ADC cytotoxin. It is utilized in synthesizing DHES0815A (an HER2 ADC) and possesses DNA-binding activity that reduces cell viability [1].
Smiles
O=C1C=2C(=CC(OCCCCCOC3=C(OC)C=C4C(=C3)N=C[C@]5(N(C4=O)CC(=C)C5)[H])=C(OC)C2)NC(=O)[C@]6(N1CC(=C)C6)[H]
Molecular Formula
C33H36N4O8
Molecular Weight
616.66
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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