Zharp1-211
Product Specifications
CAS Number
2258671-41-7
Target
STAT, RIP kinase
Related Pathways
NF-κB, Stem Cells, Apoptosis, JAK/STAT signaling
Purity
0.9971
Bioactivity
Zharp1-211 is a selective and potent RIPK3 inhibitor that significantly reduces the expression of JAK/ stat1-mediated chemokines and MHC class II molecules in IECs, restores intestinal homeostasis, and inhibits graft-versus-host disease (GVHD) for gastrointestinal inflammation.
Smiles
O=C(OC1CCOCC1)N2C=3C=C(C=NC3CC2)C=4C=CC5=NC(=CN5C4)NC(=O)C6CC6
Molecular Formula
C24H25N5O4
Molecular Weight
447.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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