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WYJ-2

Product Specifications

CAS Number

3029403-05-9

Target

Pyroptosis, TLR

Related Pathways

Immunology/Inflammation, Apoptosis

Bioactivity

WYJ-2, a selective agonist for toll-like receptor 2/1 (TLR2/1), demonstrates an EC50 of 18.57 nM in HEK 293T cells transiently co-transfected with human TLR2 and TLR1. It induces pyroptosis and has shown anticancer activity against non-small cell lung cancer (NSCLC) [1].

Smiles

FC=1C(C2=NC(=NO2)C3=CC=4C(OC3)=CC=C(F)C4)=CC(N(=O)=O)=CC1

Molecular Formula

C17H9F2N3O4

Molecular Weight

357.27

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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