WYJ-2
Product Specifications
CAS Number
3029403-05-9
Target
Pyroptosis|||TLR
Related Pathways
Immunology/Inflammation|||Apoptosis
Bioactivity
WYJ-2, a selective agonist for toll-like receptor 2/1 (TLR2/1), demonstrates an EC50 of 18.57 nM in HEK 293T cells transiently co-transfected with human TLR2 and TLR1. It induces pyroptosis and has shown anticancer activity against non-small cell lung cancer (NSCLC) [1].
Smiles
FC=1C(C2=NC(=NO2)C3=CC=4C(OC3)=CC=C(F)C4)=CC(N(=O)=O)=CC1
Molecular Formula
C17H9F2N3O4
Molecular Weight
357.27
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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