W6134
Product Specifications
CAS Number
2983540-55-0
Target
ROR
Related Pathways
Metabolism
Bioactivity
W6134 is a highly potent and selective RORγ covalent inhibitor with an IC50 of 0.21 μM. It exhibits superior activity in inhibiting proliferation and colony formation, and inducing apoptosis, making it useful for cancer research [1].
Smiles
N(C(C=C)=O)C1=C(C=CC=C1)C2=C(Cl)C=C(NC(CC3=CC=C(S(CC)(=O)=O)C=C3)=O)C=C2
Molecular Formula
C25H23ClN2O4S
Molecular Weight
482.98
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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