VL285 Phenol

Product Specifications

CAS Number

1448188-69-9

Target

Others, Ligand for E3 Ligase

Related Pathways

Others, PROTAC

Bioactivity

VL285 Phenol is an analogue of VL285 featuring a Phenol group. As a small molecule VHL ligand, VL285 serves as a degrader in HaloPROTAC3 synthesis, effectively degrading HaloTag7 fusion proteins (IC 50 = 0.34 μM) [1].

Smiles

[C@@H](C(=O)N1[C@H](C(NCC2=C(O)C=C(C=C2)C3=C(C)N=CS3)=O)C[C@@H](O)C1)([C@H](C)C)N4C(=O)C=5C(C4)=CC=CC5

Molecular Formula

C29H32N4O5S

Molecular Weight

548.65

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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