VL285 Phenol
Product Specifications
CAS Number
1448188-69-9
Target
Others|||Ligand for E3 Ligase
Related Pathways
Others|||PROTAC
Bioactivity
VL285 Phenol is an analogue of VL285 featuring a Phenol group. As a small molecule VHL ligand, VL285 serves as a degrader in HaloPROTAC3 synthesis, effectively degrading HaloTag7 fusion proteins (IC 50 = 0.34 ?M) [1].
Smiles
[C@@H](C(=O)N1[C@H](C(NCC2=C(O)C=C(C=C2)C3=C(C)N=CS3)=O)C[C@@H](O)C1)([C@H](C)C)N4C(=O)C=5C(C4)=CC=CC5
Molecular Formula
C29H32N4O5S
Molecular Weight
548.65
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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