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VISTA-IN-3

Product Specifications

CAS Number

2994662-45-0

Target

IFNAR

Related Pathways

Immunology/Inflammation

Bioactivity

VISTA-IN-3 (Compound A4), a potent small molecule inhibitor of VISTA, exhibits a dissociation constant (K D) of 0.49 μM. This compound effectively induces the release of IFN-γ cytokines and demonstrates synergistic enhancement of anti-cancer activity when combined with PD-L1 antibody [1].

Smiles

N(C=1N=C(CNCCO)C=C(OC)N1)C2=CC(O)=CC=C2

Molecular Formula

C14H18N4O3

Molecular Weight

290.32

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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