VISTA-IN-3
Product Specifications
CAS Number
2994662-45-0
Target
IFNAR
Related Pathways
Immunology/Inflammation
Bioactivity
VISTA-IN-3 (Compound A4), a potent small molecule inhibitor of VISTA, exhibits a dissociation constant (K D) of 0.49 ?M. This compound effectively induces the release of IFN-? cytokines and demonstrates synergistic enhancement of anti-cancer activity when combined with PD-L1 antibody [1].
Smiles
N(C=1N=C(CNCCO)C=C(OC)N1)C2=CC(O)=CC=C2
Molecular Formula
C14H18N4O3
Molecular Weight
290.32
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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