VDX-111
Product Specifications
CAS Number
158983-23-4
Target
Necroptosis, RIP kinase
Related Pathways
Apoptosis, NF-κB
Bioactivity
VDX-111, an analog of vitamin D, exhibits cytotoxicity in ovarian cancer cells by upregulating the RIPK1/RIPK3 pathway and inducing necroptosis. It also promotes the expression of cytokines and demonstrates antitumor activity in a mouse model [1].
Smiles
C[C@@]12[C@](\C(=C\C=C/3\C[C@@H](OC(CBr)=O)C[C@H](O)C3=C)\CCC1)(CC[C@@]2([C@@H](CCCC(C)(C)O)C)[H])[H]
Molecular Formula
C29H45BrO4
Molecular Weight
537.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
298144-01 10 µg
CCL15 (Macrophage Inflammatory Protein 5, Chemokine CC-2, C-C Motif Chemokine 15, Small-Inducible Cytokine A15)
Sign In for Pricing
View Details 298144-02 100 µg
CCL15 (Macrophage Inflammatory Protein 5, Chemokine CC-2, C-C Motif Chemokine 15, Small-Inducible Cytokine A15)
Sign In for Pricing
View Details