VDX-111
Product Specifications
CAS Number
158983-23-4
Target
Necroptosis, RIP kinase
Related Pathways
Apoptosis, NF-κB
Bioactivity
VDX-111, an analog of vitamin D, exhibits cytotoxicity in ovarian cancer cells by upregulating the RIPK1/RIPK3 pathway and inducing necroptosis. It also promotes the expression of cytokines and demonstrates antitumor activity in a mouse model [1].
Smiles
C[C@@]12[C@](\C(=C\C=C/3\C[C@@H](OC(CBr)=O)C[C@H](O)C3=C)\CCC1)(CC[C@@]2([C@@H](CCCC(C)(C)O)C)[H])[H]
Molecular Formula
C29H45BrO4
Molecular Weight
537.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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1233373 30 Pieces/Case:1 Piece/ PACKS:30 PACKS/CASE
Filter, Disk, PCTE, PVPF, 0.4μm, 8x10in, 30/Pk
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