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Vatalanib hydrochloride

Product Specifications

CAS Number

212141-52-1

Target

Apoptosis, VEGFR

Related Pathways

Angiogenesis, Apoptosis, Tyrosine Kinase/Adaptors

Purity

0.997

Bioactivity

Vatalanib hydrochloride (PTK787 hydrochloride) is an orally available and highly potent tyrosine kinase (VEGF) inhibitor that reduces the number and size of Aβ plaques in the cortex of 5xFAD mice, which may be useful in the study of Alzheimer's disease and cancer.

Smiles

Cl.ClC1=CC=C(C=C1)NC2=NN=C(C=3C=CC=CC23)CC=4C=CN=CC4

Molecular Formula

C20H16Cl2N4

Molecular Weight

383.27

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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