USP1-IN-7
Product Specifications
CAS Number
3033480-42-8
Target
DUB
Related Pathways
Ubiquitination|||DNA Damage/DNA Repair|||Cell Cycle/Checkpoint
Bioactivity
USP1-IN-7 (Compound 3), a potent inhibitor of ubiquitin specific peptidase 1 (USP1) and its cofactor UAF1, exhibits an inhibition concentration (IC 50) of ?50 nM. It also effectively inhibits the proliferation of MDA-MB-436 cells at similar concentrations [1].
Smiles
C(N1C=2C(N(C)C1=O)=CN=C(C2F)C=3C(=NC=NC3OC)C4CC4)C5=CC=C(C=C5)C6=NC(C(F)(F)F)=CN6C
Molecular Formula
C27H23F4N7O2
Molecular Weight
553.51
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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