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USP1-IN-7

Product Specifications

CAS Number

3033480-42-8

Target

DUB

Related Pathways

Ubiquitination, DNA Damage/DNA Repair, Cell Cycle/Checkpoint

Bioactivity

USP1-IN-7 (Compound 3), a potent inhibitor of ubiquitin specific peptidase 1 (USP1) and its cofactor UAF1, exhibits an inhibition concentration (IC 50) of ≤50 nM. It also effectively inhibits the proliferation of MDA-MB-436 cells at similar concentrations [1].

Smiles

C(N1C=2C(N(C)C1=O)=CN=C(C2F)C=3C(=NC=NC3OC)C4CC4)C5=CC=C(C=C5)C6=NC(C(F)(F)F)=CN6C

Molecular Formula

C27H23F4N7O2

Molecular Weight

553.51

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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