Tubulin polymerization-IN-61
Product Specifications
CAS Number
2758114-60-0
Target
Microtubule Associated|||Apoptosis
Related Pathways
Apoptosis|||Cytoskeletal Signaling
Bioactivity
Tubulin polymerization-IN-61 (Compound 9a), a tubulin polymerization inhibitor, disrupts the microtubule skeleton, arrests the cell cycle at the G2/M phase, induces Apoptosis, and impedes cancer cell migration and colony formation. This compound demonstrates antitumor efficacy in vivo within the 4T1 xenograft model [1].
Smiles
O(C)C=1C=C(N2C=3C(N=N2)=CC=C(C3)C4=CC(O)=C(OC)C=C4)C=C(OC)C1OC
Molecular Formula
C22H21N3O5
Molecular Weight
407.42
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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