Tubulin polymerization-IN-60
Product Specifications
CAS Number
2361303-91-3
Target
Apoptosis, Microtubule Associated
Related Pathways
Cytoskeletal Signaling, Apoptosis
Bioactivity
Tubulin polymerization-IN-60 (BF3), a colchicine binding site inhibitor (CBSIs), effectively inhibits tubulin polymerization and exhibits anticancer properties. It disrupts cell cycle progression, induces G2/M arrest, and triggers apoptosis [1].
Smiles
C(=O)(C=1C=2C(OC1C3=CC=CC=C3)=C(OC)C=CC2)C4=CC(OC)=C(OC)C(OC)=C4
Molecular Formula
C25H22O6
Molecular Weight
418.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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