Topoisomerase II inhibitor 18
Selected Variant
T87552-01
Size: 10 mg
Product Specifications
CAS Number
2382959-65-9
Target
Topoisomerase
Related Pathways
DNA Damage/DNA Repair
Bioactivity
Topoisomerase II inhibitor 18 (Compound IV), a Quinoxaline derivative, exhibits an IC 50 of 7.5 μM in inhibiting topoisomerase II. It impedes PC-3 cell proliferation, arrests the cell cycle at the S phase, and induces apoptosis. Moreover, this compound demonstrates substantial antitumor activity against cancer [1].
Smiles
S(CCC(NCCC)=O)C=1C(=NC2=C(N1)C=CC=C2)C3=CC=CC=C3
Molecular Formula
C20H21N3OS
Molecular Weight
351.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Price
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