Topoisomerase II inhibitor 18
Selected Variant
T87552-01
Size: 10 mg
Product Specifications
CAS Number
2382959-65-9
Target
Topoisomerase
Related Pathways
DNA Damage/DNA Repair
Bioactivity
Topoisomerase II inhibitor 18 (Compound IV), a Quinoxaline derivative, exhibits an IC 50 of 7.5 μM in inhibiting topoisomerase II. It impedes PC-3 cell proliferation, arrests the cell cycle at the S phase, and induces apoptosis. Moreover, this compound demonstrates substantial antitumor activity against cancer [1].
Smiles
S(CCC(NCCC)=O)C=1C(=NC2=C(N1)C=CC=C2)C3=CC=CC=C3
Molecular Formula
C20H21N3OS
Molecular Weight
351.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Price
Sign In for Pricing
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNUB2829-500 1x 500 µL
Golgi Complex (Marker for Human Cells) (GLG1/2829R), 0.2mg/mL
Sign In for Pricing
View Details 
BNCB0882-500 1x 500 µL
Androgen Receptor (DHTR/882), Biotin conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
PB9893-Dylight550 100 µg
Anti-SMYD3 Antibody Picoband® (Dylight550 Conjugate)
Sign In for Pricing
View Details 
BNCB2603-100 1x 100 µL
Calretinin / Calbindin 2 (Mesothelioma Marker) (CALB2/2603), Biotin conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
A00516-3-Dylight550 100 µg
Anti-PON1 Antibody Picoband®, Dylight550 Conjugate
Sign In for Pricing
View Details 
BNC472242-100 1x 100 µL
Glutathione S-Transferase Mu2 (GSTM2) (CPTC-GSTMu2-2), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details