Thalidomide-PIP- (R) C-pyrrolidine-boc
Product Specifications
CAS Number
2839668-87-8
Target
Autophagy, Ligand for E3 Ligase
Related Pathways
PROTAC, Autophagy
Bioactivity
Thalidomide-PIP- (R) C-pyrrolidine-boc is a conjugate comprising an E3 ligase ligand and a linker, specifically containing Thalidomide and its corresponding linker. This compound functions as a Cereblon ligand, facilitating the recruitment of the CRBN protein, and is a crucial intermediate in synthesizing complete PROTAC molecules.
Smiles
O=C1N(C(=O)C=2C1=CC(=CC2)N3CCN(C[C@@H]4CN(C(OC(C)(C)C)=O)CC4)CC3)C5C(=O)NC(=O)CC5
Molecular Formula
C27H35N5O6
Molecular Weight
525.6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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