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Thalidomide-azetidine-C-PIP-C-boc

Product Specifications

CAS Number

2589699-87-4

Target

Ligand for E3 Ligase, Autophagy

Related Pathways

Autophagy, PROTAC

Bioactivity

Thalidomide-azetidine-C-PIP-C-boc is a conjugate of E3 ligase ligand and linker, comprising Thalidomide and the corresponding linker. As a Cereblon ligand, Thalidomide-azetidine-C-PIP-C-boc recruits CRBN protein and acts as a crucial intermediate in the synthesis of complete PROTAC molecules.

Smiles

O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=C(C2)N4CC(CN5CCN(CC(OC(C)(C)C)=O)CC5)C4

Molecular Formula

C27H35N5O6

Molecular Weight

525.6

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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