Thalidomide-azetidine-C-PIP-C-boc
Product Specifications
CAS Number
2589699-87-4
Target
Ligand for E3 Ligase|||Autophagy
Related Pathways
Autophagy|||PROTAC
Bioactivity
Thalidomide-azetidine-C-PIP-C-boc is a conjugate of E3 ligase ligand and linker, comprising Thalidomide and the corresponding linker. As a Cereblon ligand, Thalidomide-azetidine-C-PIP-C-boc recruits CRBN protein and acts as a crucial intermediate in the synthesis of complete PROTAC molecules.
Smiles
O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=C(C2)N4CC(CN5CCN(CC(OC(C)(C)C)=O)CC5)C4
Molecular Formula
C27H35N5O6
Molecular Weight
525.6
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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