T3SS-IN-4

T3SS-IN-4 (Compound Z-8) serves as an inhibitor specifically targeting the Type III secretion system (T3SS) of Xanthomonas oryzae pv oryzae (X oo), effectively curbing the expression of T3SS-related genes without impeding bacterial growth. This compound not only diminishes the hypersensitive response (HR) triggered by X oo in tobacco but also reduces the pathogenicity of X oo in rice [1].