T-1-PMPA

Product Specifications

CAS Number

1323883-62-0

Target

EGFR|||Apoptosis

Related Pathways

Apoptosis|||JAK/STAT signaling|||Angiogenesis|||Tyrosine Kinase/Adaptors

Bioactivity

T-1-PMPA, a potent EGFR inhibitor, demonstrates apoptotic properties and effectively inhibits EGFR WT and EGFR 790m, with IC50 values of 86 nM and 561.73 nM, respectively [1].

Smiles

O=C1C2=C(N(C)C(=O)N1CC(NC3=CC=C(C)C=C3)=O)N=CN2C

Molecular Formula

C16H17N5O3

Molecular Weight

327.34

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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