SIQ17
Product Specifications
CAS Number
2151881-74-0
Target
EGFR
Related Pathways
Angiogenesis, JAK/STAT signaling, Tyrosine Kinase/Adaptors
Bioactivity
SIQ17, an EGFR inhibitor, blocks the ATP-binding site with an IC50 of 0.62 nM, demonstrating more effective EGFR-TK inhibitory activity than the known inhibitor Erlotinib (IC50 of ∼20 nM) . SIQ17 is applicable in cancer research [1].
Smiles
S(=O)(=O)(C1=C2C(C=3C1=CC=CC3)=C(N(C)C=4C2=CC=CC4)C5=C(C)C=C(C)C=C5)C6=CC=C(C)C=C6
Molecular Formula
C32H27NO2S
Molecular Weight
489.63
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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