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Sigma-2 Radioligand 1

Product Specifications

CAS Number

2860554-32-9

Target

Sigma receptor

Related Pathways

GPCR/G Protein

Bioactivity

Sigma-2 Radioligand 1 (compound 1) serves as a selective Sigma-2 ligand, demonstrating favorable biodistribution in mice and robust in vivo activity in rats. The [18F] modified version of Sigma-2 Radioligand 1 enhances the visualization of tumors in micro-PET/CT imaging by providing high tumor uptake and an impressive tumor-to-background ratio. Additionally, experiments confirm that this compound binds with high specificity to U87MG glioma xenografts [1].

Smiles

C(CCCN1CC=2C(CC1)=CC(OC)=C(OC)C2)N3C=4C(N(CCF)C3=O)=CC=CC4

Molecular Formula

C24H30FN3O3

Molecular Weight

427.51

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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