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SEH/HDAC6-IN-1

Product Specifications

CAS Number

2847838-67-7

Target

Epoxide Hydrolase, HDAC

Related Pathways

Chromatin/Epigenetic, DNA Damage/DNA Repair, Metabolism

Bioactivity

SEH/HDAC6-IN-1 (compound M9) serves as a selective, orally active dual inhibitor targeting both sEH and HDAC6. It demonstrates IC50 values of 2 nM for human sEH, 0.72 nM for murine sEH, and 5 nM for HDAC6. Notably, sEH/HDAC6-IN-1 exhibits analgesic and anti-inflammatory effects [1].

Smiles

N(C(NC1=CC=C(C(NCCCCCCC(NO)=O)=O)C=C1)=O)C23CC4(C)CC(C)(C2)CC(C3)C4

Molecular Formula

C27H40N4O4

Molecular Weight

484.63

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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