SEH/HDAC6-IN-1
Product Specifications
CAS Number
2847838-67-7
Target
Epoxide Hydrolase|||HDAC
Related Pathways
Chromatin/Epigenetic|||DNA Damage/DNA Repair|||Metabolism
Bioactivity
SEH/HDAC6-IN-1 (compound M9) serves as a selective, orally active dual inhibitor targeting both sEH and HDAC6. It demonstrates IC50 values of 2 nM for human sEH, 0.72 nM for murine sEH, and 5 nM for HDAC6. Notably, sEH/HDAC6-IN-1 exhibits analgesic and anti-inflammatory effects [1].
Smiles
N(C(NC1=CC=C(C(NCCCCCCC(NO)=O)=O)C=C1)=O)C23CC4(C)CC(C)(C2)CC(C3)C4
Molecular Formula
C27H40N4O4
Molecular Weight
484.63
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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