SB 206553
Product Specifications
CAS Number
158942-04-2
Target
5-HT Receptor
Related Pathways
Neuroscience|||GPCR/G Protein
Bioactivity
SB 206553 is a 5-HT2C inverse agonist that can attenuate methamphetamine-seeking behavior in rats. It exhibits activity for 5-HT2 receptor ligands with pKi values of 5.6 nM (5-HT2A), 7.7 nM (5-HT2B), and 7.8 nM (5-HT2C) in HEK-293 or CHO-K1 cells expressing human recombinant 5-HT2 receptors. SB 206553 can be used for research into psychostimulant abuse disorders [1].
Smiles
C(NC=1C=CC=NC1)(=O)N2C=3C(=CC4=C(C3)C=CN4C)CC2
Molecular Formula
C17H16N4O
Molecular Weight
292.34
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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