PROTAC SOS1 degrader-5
Product Specifications
CAS Number
2836273-61-9
Target
Ras, PROTACs
Related Pathways
MAPK, PROTAC, GPCR/G Protein
Bioactivity
PROTAC SOS1 degrader-5 (compound 4) serves as an effective degrader of PROTAC SOS1, exhibiting a DC50 of 13 nM. It robustly suppresses the proliferation of NCI-H358 cells, with an IC50 value of 5 nM [1].
Smiles
C(OC1=CC2=C(C=C1OC)N=C(C)N=C2N[C@H](C)C3=CC(C(F)(F)F)=CC(N)=C3)C4(CN(C(CCCCCCNC5=C6C(C(=O)N(C6=O)C7C(=O)NC(=O)CC7)=CC=C5)=O)C)CC4
Molecular Formula
C45H51F3N8O7
Molecular Weight
872.93
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC403498-100 1x 100 µL
PAI-RBP1 / SERBP1 / SERPINE1 (SERBP1/3498), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
22668-AAT 500 Assays
Cell Navigator® Mitochondrion Staining Kit *Red Fluorescence*
Sign In for Pricing
View Details 
![(R)-1-[(SP)-2-(Dicyclohexylphosphino)ferrocenyl]ethyldi-tert-butylphosphine](https://cdn.genprice.uk/products/572/7235414508340/imageurl/trc-d439235-50mg.webp)
TRC-D439235-50MG 50 mg
(R)-1-[(SP)-2-(Dicyclohexylphosphino)ferrocenyl]ethyldi-tert-butylphosphine
Sign In for Pricing
View Details 
E-UNEL-H0390-01 5x 96 Tests
Uncoated Human CD38 (Cyclic ADP Ribose Hydrolase) ELISA Kit
Sign In for Pricing
View Details