PROTAC ER? Degrader-8

3025533-68-7

PROTACs|||Estrogen Receptor/ERR

PROTAC|||Endocrinology/Hormones

PROTAC ER? Degrader-8 (compound ii-56), a highly potent degrader of Er?, achieves a DC50 of just 0.000006 ?M in MCF7 cells [1].

OC=1C=C2C([C@@H]([C@@H](CC2)C3=CC=CC=C3)C4=CC=C(C=C4)N5C6(CC(CN7CCN(CC7)C=8C=C9C(=CC8)C(=O)N(C9)[C@@H]%10C(=O)NC(=O)CC%10)CC5(CC6)[H])[H])=CC1

C47H51N5O4

749.94

Cool pack

-20°C