PROTAC Chk1 degrader-1
Product Specifications
CAS Number
2597167-34-3
Target
PROTACs, Chk
Related Pathways
Cell Cycle/Checkpoint, PROTAC
Bioactivity
Compound PROTAC-2, also known as PROTAC Chk1 degrader-1, is a potent degrader of Chk1, exhibiting a DC50 of 1.33 μM. It is utilized in cancer research [1].
Smiles
O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2OCC(NCCOCCOCCN4C=C(CNC(=O)C=5C=C(NC=6C=C(NN6)C7CC7)N=C(NC8=CC=C(CC#N)C=C8)N5)N=N4)=O
Molecular Formula
C43H44N14O9
Molecular Weight
900.9
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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